Nowadays, surgeons have different types of materials available. There is autologous bone, the patient's own bone that is taken from sites in the mouth in order to restore missing volume. Such bone has excellent viability but can undergo resorption if not used properly. Then we have homologous bone, that of cadaveric origin, which under strong controls comes to be used in the mouth. Such bone does not have the same capacity as autologous bone depriving itself after sterilization procedures of many characteristics. Italian regulations in this regard are fortunately very strict. In addition, there are products of animal or plant origin that can be used only under special conditions, as they lack properties that only autologous bone possesses.